2-(2-Bromoethyl)oxane → HCID 57699626, compound

HRID 1011112Notes

Reaction equation

HRID 1011112 reaction equation
FC(F)(F)C(O)=O.[CH:8]1([CH2:11][CH2:12][O:13][C:14]2[NH:15][C:16]([NH2:25])=[C:17]3[C:21]([N:22]=2)=[N:20][C:19]([O:23][CH3:24])=[N:18]3)[CH2:10][CH2:9]1.Br[CH2:27][CH2:28][CH:29]1[CH2:34][CH2:33][CH2:32][CH2:31][O:30]1>>[CH:8]1([CH2:11][CH2:12][O:13][C:14]2[N:22]=[C:21]3[C:17]([N:18]=[C:19]([O:23][CH3:24])[N:20]3[CH2:27][CH2:28][CH:29]3[CH2:34][CH2:33][CH2:32][CH2:31][O:30]3)=[C:16]([NH2:25])[N:15]=2)[CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 127915862-(2-Bromoethyl)oxaneHCID 178494009HCID 178494009, compound

Product 1

HCID 57699626HCID 57699626, compound

Procedure

Prepared similarly to Intermediate 216 from 2-[(2-cyclopropylethyl)oxy]-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 2-(2-bromoethyl)tetrahydro-2H-pyran.

Sources & evidence

ORD record
ord-1c71f07ca6df4965aff1cd820b06ea45
Source dataset
uspto-grants-2011_07
Patent number
US07977344B2

Reaction notes

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