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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011115Generated: November 2, 2026

3-(2-Bromoethyl)tetrahydro-2H-pyran → 2-[(2-Cyclopropylethyl)oxy]-8-(methyloxy)-9-[2-(tetrahydro-2H-Pyran-3-yl)ethyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011115

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Bromoethyl)tetrahydro-2H-pyranHCID 54494306—
ReactantHCID 178494009HCID 178494009—
Product2-[(2-Cyclopropylethyl)oxy]-8-(methyloxy)-9-[2-(tetrahydro-2H-Pyran-3-yl)ethyl]-9H-purin-6-amineHCID 57699750—

Reaction Steps

Prepared similarly to Intermediate 216 from 2-[(2-cyclopropylethyl)oxy]-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 3-(2-bromoethyl)tetrahydro-2H-pyran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-9fd84132dc9f4b5f81e1359141b1224a
Source noteuspto-grants-2011_07