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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011117Generated: October 26, 2026

4-(2-Bromoethyl)oxane → 2-[(2-Cyclopropylethyl)oxy]-8-(methyloxy)-9-[2-(tetrahydro-2H-Pyran-4-yl)ethyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011117

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Bromoethyl)oxaneHCID 22637012—
ReactantHCID 178494009HCID 178494009—
Product2-[(2-Cyclopropylethyl)oxy]-8-(methyloxy)-9-[2-(tetrahydro-2H-Pyran-4-yl)ethyl]-9H-purin-6-amineHCID 57699662—

Reaction Steps

Prepared similarly to Intermediate 215 from 2-[(2-cyclopropylethyl)oxy]-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 4-(2-bromoethyl)tetrahydro-2H-pyran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-21b8b066a7564c1d9f18c6be5ca5cee2
Source noteuspto-grants-2011_07