1050496-76-8 → HCID 57699759, compound

HRID 1011119Notes

Reaction equation

HRID 1011119 reaction equation
FC(F)(F)C(O)=O.[CH:8]1([CH2:11][CH2:12][O:13][C:14]2[NH:15][C:16]([NH2:25])=[C:17]3[C:21]([N:22]=2)=[N:20][C:19]([O:23][CH3:24])=[N:18]3)[CH2:10][CH2:9]1.Br[CH2:27][CH2:28][CH2:29][CH2:30][CH:31]1[CH2:36][CH2:35][O:34][CH2:33][CH2:32]1>>[CH:8]1([CH2:11][CH2:12][O:13][C:14]2[N:22]=[C:21]3[C:17]([N:18]=[C:19]([O:23][CH3:24])[N:20]3[CH2:27][CH2:28][CH2:29][CH2:30][CH:31]3[CH2:36][CH2:35][O:34][CH2:33][CH2:32]3)=[C:16]([NH2:25])[N:15]=2)[CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 576997011050496-76-8HCID 178494009HCID 178494009, compound

Product 1

HCID 57699759HCID 57699759, compound

Procedure

Prepared similarly to Intermediate 220 from 2-[(2-cyclopropylethyl)oxy]-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 4-(4-bromobutyl)tetrahydro-2H-pyran.

Sources & evidence

ORD record
ord-b11113cc93974494ac6604be7c7005ee
Source dataset
uspto-grants-2011_07
Patent number
US07977344B2

Reaction notes

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