1050496-83-7 → HCID 57699643, compound

HRID 1011120Notes

Reaction equation

HRID 1011120 reaction equation
FC(F)(F)C(O)=O.[CH:8]1([CH2:11][CH2:12][O:13][C:14]2[NH:15][C:16]([NH2:25])=[C:17]3[C:21]([N:22]=2)=[N:20][C:19]([O:23][CH3:24])=[N:18]3)[CH2:10][CH2:9]1.Br[CH2:27][CH2:28][CH:29]1[CH2:34][CH2:33][O:32][C:31]([CH3:36])([CH3:35])[CH2:30]1>>[CH:8]1([CH2:11][CH2:12][O:13][C:14]2[N:22]=[C:21]3[C:17]([N:18]=[C:19]([O:23][CH3:24])[N:20]3[CH2:27][CH2:28][CH:29]3[CH2:34][CH2:33][O:32][C:31]([CH3:36])([CH3:35])[CH2:30]3)=[C:16]([NH2:25])[N:15]=2)[CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 576997121050496-83-7HCID 178494009HCID 178494009, compound

Product 1

HCID 57699643HCID 57699643, compound

Procedure

Prepared similarly to Intermediate 216 from 2-[(2-cyclopropylethyl)oxy]-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 4-(2-bromoethyl)-2,2-dimethyltetrahydro-2H-pyran.

Sources & evidence

ORD record
ord-b251b0b68e424cd0b23376fa0faa6b7e
Source dataset
uspto-grants-2011_07
Patent number
US07977344B2

Reaction notes

Loading…