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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011123Generated: November 3, 2026

2-(2-Bromoethyl)oxolane → 2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[2-(tetrahydro-2-furanyl)ethyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011123

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Bromoethyl)oxolaneHCID 53691871—
ReactantHCID 178448285HCID 178448285—
Product2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[2-(tetrahydro-2-furanyl)ethyl]-9H-purin-6-amineHCID 57699659—

Reaction Steps

Prepared similarly to Intermediate 243 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 2-(2-bromoethyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-cbcb6d396e1c48c4805285df1d9db494
Source noteuspto-grants-2011_07