Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011135Generated: October 27, 2026

3-(3-Bromopropyl)oxolane → 2-{[(1R)-1-methylbutyl]oxy}-8-(methyloxy)-9-[3-(tetrahydro-3-furanyl)propyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011135

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Bromopropyl)oxolaneHCID 57699778—
ReactantHCID 178448284HCID 178448284—
Product2-{[(1R)-1-methylbutyl]oxy}-8-(methyloxy)-9-[3-(tetrahydro-3-furanyl)propyl]-9H-purin-6-amineHCID 57699740—

Reaction Steps

Prepared similarly to Intermediate 216 from 2-{[(1R)-1-methylbutyl]oxy}-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 3-(3-bromopropyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-673174fd2e3342d49383a1bb2a3aaf34
Source noteuspto-grants-2011_07