Hydrochloric Acid → HCID 25024974, compound

Participants

Reaction Steps

2-Butoxy-8-methoxy-9-(tetrahydro-2H-pyran-2-ylmethyl)-9H-purin-6-amine (6 mg, 85% pure) was dissolved in methanol (1 mL), treated with 4N hydrogen chloride in 1,4-dioxane (0.5 mL) and stirred for 5 hours at room temperature. The mixture was stripped to dryness to give the title compound (77.8:10.8 by LCMS) as a colourless gum (8 mg).

Provenance & Evidence