1-(4-(bromomethyl)phenyl)-1H-1,2,4-triazole → 4-methyl-2-[1-(4-[1,2,4]triazol-1-yl-benzyl)-1H-pyrazol-3-yl]-thiazole-5-carboxylic acid (pyridin-3-ylmethyl)amide

HRID 101130Notes

Reaction equation

HRID 101130 reaction equation
[Br:22][CH2:23][c:24]1[cH:25][cH:26][c:27](-[n:30]2[n:31][cH:32][n:33][cH:34]2)[cH:28][cH:29]1.[n:1]1[cH:2][c:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]2[c:12]([CH3:21])[n:13][c:14](-[c:16]3[nH:17][n:18][cH:19][cH:20]3)[s:15]2)[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]2[c:12]([CH3:21])[n:13][c:14](-[c:16]3[n:17][n:18]([CH2:23][c:24]4[cH:25][cH:26][c:27](-[n:30]5[n:31][cH:32][n:33][cH:34]5)[cH:28][cH:29]4)[cH:19][cH:20]3)[s:15]2)[cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 27764891-(4-(bromomethyl)phenyl)-1H-1,2,4-triazoleHCID 866455594-methyl-2-(2H-pyrazol-3-yl)-thiazole-5-carboxylic acid (pyridin-3-ylmethyl)-amide

Product 1

HCID 249568474-methyl-2-[1-(4-[1,2,4]triazol-1-yl-benzyl)-1H-pyrazol-3-yl]-thiazole-5-carboxylic acid (pyridin-3-ylmethyl)amide

Sources & evidence

ORD record
ord-efcfae6be856479199628365c076f266
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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