(2-Methoxyethyl)(methyl)amine → HCID 58478749, compound

HRID 1011375Notes

Reaction equation

HRID 1011375 reaction equation
[O:1]=[C:2]1[C:10]2[C:5](=[N:6][C:7]([CH2:11][CH2:12][CH:13]=O)=[CH:8][CH:9]=2)[CH2:4][O:3]1.[CH3:15][O:16][CH2:17][CH2:18][NH:19][CH3:20]>>[CH3:15][O:16][CH2:17][CH2:18][N:19]([CH3:20])[CH2:13][CH2:12][CH2:11][C:7]1[N:6]=[C:5]2[CH2:4][O:3][C:2](=[O:1])[C:10]2=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 300977(2-Methoxyethyl)(methyl)amineHCID 58478730HCID 58478730, compound

Product 1

HCID 58478749HCID 58478749, compoundYield 85.1%

Procedure

In a process similar to that described in Preparation 8, 3-(5-Oxo-5,7-dihydro-furo[3,4-b]pyridin-2-yl)-propionaldehyde (76 mg, 0.4 mmol) and N-(2-methoxyethyl)methylamine (43 μL, 0.4 mmol) are reacted to provide the title compound as pale yellow oil (90 mg, 85%).

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-dd3be28d50bb44018e44430d45a8809c
Source dataset
uspto-grants-2011_07
Patent number
US07977351B2

Reaction notes

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