Ammonium formate → HCID 67315438, compound

Participants

Reaction Steps

A solution of 3-(6-Chloro-1-ethyl-1H-furo[3,4-c]pyridin-3-ylidene)-5-fluoro-1,3-dihydro-indol-2-one (50 mg, 0.15 mmol) in 8 ml ethanol is treated with 50 mg of 5% Pd/C and ammonium formate (500 mg). The reaction mixture is stirred for 24 h at room temperature. The reaction mixture is concentrated and is then loaded onto silica gel and purified using 5% MeOH-EtOAc. The product containing fractions are concentrated to give the title compound (18 mg, 40%).

Provenance & Evidence