HCID 25005708, compound → HCID 59285935, compound

Participants

Reaction Steps

5% Palladium on activated carbon (30 mg) was added to a solution of 2-aminocarbonylamino-5-(3-nitrophenyl)pyrrole-3-carboxamide (Compound No. 1-6, 0.15 g, 0.52 mmol) in methanol (10 mL) and the mixture was stirred at room temperature for 6.5 hours under hydrogen gas atmosphere. After the insoluble solid was filtered out, the solvent was removed under reduced pressure. The obtained solid was washed with a mixed solvent (6 mL) which consists of chloroform and methanol (5:1), and dried under reduced pressure to give the target compound (0.072 g) as a pale yellow solid (Yield 53%).

Provenance & Evidence