反应详情

1-butyl-N,N-dimethyl-4,4-bis(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine (100 mg, 0.17 mmol) was dissolved in ethanol (10 ml) and mixed with citric acid (36 mg, 0.187 mmol) dissolved in hot ethanol (3 ml). The clear colourless solution was stirred for 48 h and then concentrated to low volume. After adding diethyl ether (10 ml), the mixture was stirred for 2 h at RT and the precipitate was then aspirated.

1. concentrationconcentrated to low volume
2. additionAfter adding diethyl ether (10 ml)
3. stirringthe mixture was stirred for 2 h at RT