Water → HCID 66911563, compound

Participants

Reaction Steps

Tryptamine (3.09 g; 19 mmol) was dissolved in toluol (300 ml). Phthalic anhydride (3 g; 20.2 mmol) was then added. The yellow reaction solution was boiled with reflux for 7 h (water separator). The course of the reaction was controlled by DC. For work up toluol was distilled off completely. The remaining yellow solid was recrystallised from cyclohexane/chloroform (1:1). 4.796 g (90%) of the product were obtained.

Provenance & Evidence