Chlorotrimethylsilane → HCID 67313267, compound

Participants

Reaction Conditions

Reaction Steps

1-butyl-4,4-bis-(1,3-dimethyl-1H-indol-2-yl)-N,N-dimethylcyclohexylamine (39 mg, 0.083 mmol) was dissolved in cyclohexane (10 ml). The solution was mixed with chlorotrimethyl silane (20 μl, 0.156 mmol) at 24° C. The clear reaction mixture immediately became cloudy. The mixture was stirred for 30 min at 24° C. The white precipitate was aspirated. The solid was washed with cyclohexane (3×0.5 ml) and then dried. The hydrochloride (40 mg, 95%, melting point 153-157° C.) was obtained as a white solid.

Provenance & Evidence