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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011656Generated: November 1, 2026

(4-Bromo-3-fluorophenyl)methanol → 4-Bromo-3-fluorobenzaldehyde

https://huagongshe.com/reaction/1011656

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Bromo-3-fluorophenyl)methanolHCID 20682297—
CatalystHCID 178418406HCID 178418406—
SolventChloroformHCID 6212—
Product4-Bromo-3-fluorobenzaldehydeHCID 278341155%

Reaction Steps

To a solution of (4-bromo-3-fluoro-phenyl)-methanol (4.3 g, 21 mmol) in CHCl3 (50 mL) was added manganese dioxide (18.7 g, 210 mmol), and the resulting mixture was stirred overnight at room temperature until the starting material had been consumed. After filtration, the filtrate was concentrated in vacuo to give product (2.3 g, 55%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977372B2
Source datasetuspto-grants-2011_07
ORD IDord-76505d636f0c43e69ebf98ed7551d779
Source noteuspto-grants-2011_07