HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Bromo-3-fluorophenyl)methanol → 4-Bromo-3-fluorobenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Bromo-3-fluorophenyl)methanol | HCID 20682297 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-Bromo-3-fluorobenzaldehyde | HCID 2783411 | 55% |
Reaction Steps
To a solution of (4-bromo-3-fluoro-phenyl)-methanol (4.3 g, 21 mmol) in CHCl3 (50 mL) was added manganese dioxide (18.7 g, 210 mmol), and the resulting mixture was stirred overnight at room temperature until the starting material had been consumed. After filtration, the filtrate was concentrated in vacuo to give product (2.3 g, 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977372B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-76505d636f0c43e69ebf98ed7551d779 |
| Source note | uspto-grants-2011_07 |