HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011853Generated: November 3, 2026
Sodium Hydroxide → 2H-Azepin-2-one, 3-aminohexahydro-
https://huagongshe.com/reaction/1011853
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | L-Lysine monohydrochloride | HCID 69568 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2H-Azepin-2-one, 3-aminohexahydro- | HCID 102463 | — |
Reaction Steps
50 mmols of L-lysine hydrochloride 1 is neutralized with 50 mmols of NaOH and then 200 ml of ethanol is added. This mixture is heated to 200° C. for eight hours. The yield of α-amino-ε-caprolactam 2 produced by this reaction is about 47%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07977450B2 |
|---|
| Source dataset | uspto-grants-2011_07 |
|---|
| ORD ID | ord-a57d2f47ef044e78a816387fffab62a6 |
|---|
| Source note | uspto-grants-2011_07 |
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