Sodium Hydroxide → HCID 67316097, compound

HRID 1011876Notes

Reaction equation

HRID 1011876 reaction equation
C([O:3][C:4]([C:6]1[C:7]([CH:23]2[CH2:25][CH2:24]2)=[N:8][N:9]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([O:18][C:19]([F:22])([F:21])[F:20])[CH:13]=2)[C:10]=1[CH3:11])=[O:5])C.[OH-].[Na+]>>[CH:23]1([C:7]2[C:6]([C:4]([OH:5])=[O:3])=[C:10]([CH3:11])[N:9]([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([O:18][C:19]([F:21])([F:22])[F:20])[CH:13]=3)[N:8]=2)[CH2:25][CH2:24]1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 67314879HCID 67314879, compound

Product 1

HCID 67316097HCID 67316097, compound

Procedure

The title compound was prepared from 3-Cyclopropyl-5-methyl-1-(3-trifluoromethoxy-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester by hydrolysis with sodium hydroxide in analogy to intermediate 6. MS: 327.1 (MH+).

Sources & evidence

ORD record
ord-c3d69d2b8f3e45d598704649593b1847
Source dataset
uspto-grants-2011_07
Patent number
US07977358B2

Reaction notes

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