3-(Diethylamino)pyrrolidine → [Rac]-(1-{3-[(e)-2-(4-chloro-phenyl)-vinyl]-phenyl}-3,5-diethyl-1h-pyrazol-4-yl)-(3-diethylamino-pyrrolidin-1-yl)-methanone

Participants

Role	Name	HCID	Charge
Reactant	3-(Diethylamino)pyrrolidine	HCID 19961995	—
Reactant	1-{3-[(E)-2-(4-Chloro-phenyl)-vinyl]-phenyl}-3,5-diethyl-1H-pyrazole-4-carboxylic acid	HCID 67313975	—
Product	[Rac]-(1-{3-[(e)-2-(4-chloro-phenyl)-vinyl]-phenyl}-3,5-diethyl-1h-pyrazol-4-yl)-(3-diethylamino-pyrrolidin-1-yl)-methanone	HCID 57555065	—

Reaction Steps

In analogy to the procedure described for example 2, 1-{3-[(E)-2-(4-chloro-phenyl)-vinyl]-phenyl}-3,5-diethyl-1H-pyrazole-4-carboxylic acid (intermediate 1) and [rac]-diethyl-pyrrolidin-3-yl-amine gave the title compound as colorless oil. MS: 505.3 (MH+, 1 Cl).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07977358B2
Source dataset	uspto-grants-2011_07
ORD ID	ord-b5bd23f8e71647e588fe80ea173f0a52
Source note	uspto-grants-2011_07