3-(Diethylamino)pyrrolidine → HCID 57554949, compound

HRID 1011893Notes

Reaction equation

HRID 1011893 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([N:16]3[C:20]([CH2:21][O:22][CH3:23])=[C:19]([C:24](O)=[O:25])[C:18]([CH2:27][O:28][CH3:29])=[N:17]3)[CH:13]=[CH:14][CH:15]=2)=[CH:4][CH:3]=1.[CH2:30]([N:32]([CH2:38][CH3:39])[CH:33]1[CH2:37][CH2:36][NH:35][CH2:34]1)[CH3:31]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([N:16]3[C:20]([CH2:21][O:22][CH3:23])=[C:19]([C:24]([N:35]4[CH2:36][CH2:37][CH:33]([N:32]([CH2:38][CH3:39])[CH2:30][CH3:31])[CH2:34]4)=[O:25])[C:18]([CH2:27][O:28][CH3:29])=[N:17]3)[CH:13]=[CH:14][CH:15]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 199619953-(Diethylamino)pyrrolidineHCID 67314229HCID 67314229, compound2×

Product 1

HCID 57554949HCID 57554949, compound

Procedure

In analogy to the procedure described for example 1, 1-{3-[(E)-2-(4-chloro-phenyl)-vinyl]-phenyl}-3,5-bis-methoxymethyl-1H-pyrazole-4-carboxylic acid (intermediate 3) and [rac]-diethyl-pyrrolidin-3-yl-amine gave the title compound as brown solid. MS: 537.3 (MH+, 1 Cl).

Sources & evidence

ORD record
ord-e9961fab680e415ca6e0ecb0aad8ca27
Source dataset
uspto-grants-2011_07
Patent number
US07977358B2

Reaction notes

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