HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo[b]furan-2-boronic acid → [5-(3-Benzofuran-2-yl-phenyl)-2,4-dimethyl-2H-pyrazol-3-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo[b]furan-2-boronic acid | HCID 2776266 | — |
| Reactant | [5-(3-Bromo-phenyl)-2,4-dimethyl-2H-pyrazol-3-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanone | HCID 67314617 | — |
| Product | [5-(3-Benzofuran-2-yl-phenyl)-2,4-dimethyl-2H-pyrazol-3-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanone | HCID 67313967 | 36% |
Reaction Steps
In analogy to the procedure described in Example 14C], [5-(3-bromo-phenyl)-2,4-dimethyl-2H-pyrazol-3-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanone and benzo[b]furan-2-boronic acid gave the title compound in 36% yield as yellow foam. MS: 457.4 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977358B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-82d0b158de0a4fa0b20843521a484e19 |
| Source note | uspto-grants-2011_07 |