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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011916Generated: October 26, 2026

1-(3-Bromophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid → [1-(3-Bromo-phenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanone

https://huagongshe.com/reaction/1011916

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Bromophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acidHCID 2763997—
Reactant3-(Diethylamino)pyrrolidineHCID 19961995—
Product[1-(3-Bromo-phenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanoneHCID 6731379561%

Reaction Steps

In analogy to the procedure described in example 12D], 1-(3-bromo-phenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid and 3-(diethylamino)pyrrolidine gave the title compound in 61% yield as brown viscous oil. MS: 419.2 (MH+, 1 Br).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977358B2
Source datasetuspto-grants-2011_07
ORD IDord-c4300c4424d042559fff4078a37aabac
Source noteuspto-grants-2011_07