HCID 19693966, compound → 4-[4-(4-(3,6-Dioxaoctyloxy)-phenyl)cyclohexylamino]-3-chloro-2-methylpyridine

HRID 1012Notes

Reaction equation

HRID 1012 reaction equation
[Cl:1][C:2]1[C:3]([CH3:9])=[N:4][CH:5]=[CH:6][C:7]=1Cl.[CH2:10]([O:18][C:19]1[CH:24]=[CH:23][C:22]([CH:25]2[CH2:30][CH2:29][CH:28]([NH2:31])[CH2:27][CH2:26]2)=[CH:21][CH:20]=1)[CH2:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH3:17]>>[CH2:10]([O:18][C:19]1[CH:20]=[CH:21][C:22]([CH:25]2[CH2:30][CH2:29][CH:28]([NH:31][C:7]3[CH:6]=[CH:5][N:4]=[C:3]([CH3:9])[C:2]=3[Cl:1])[CH2:27][CH2:26]2)=[CH:23][CH:24]=1)[CH2:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH3:17]

Participants

3

Reactant 2

HCID 19693966HCID 19693966, compoundHCID 219228903,4-Dichloro-2-methylpyridine

Product 1

HCID 196939674-[4-(4-(3,6-Dioxaoctyloxy)-phenyl)cyclohexylamino]-3-chloro-2-methylpyridineYield 28%

Procedure

Preparation was carried out analogously to Example 35 from 3,4-dichloro-2-methylpyridine and 4-(4-(3,6-dioxaoctyloxy)phenyl)cyclohexylamine. After 4.5 hours the mixture is worked up. Yield: 28%

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-d4704ef73c974a1ead59af967133bf07
Source dataset
uspto-grants-1998_03
Patent number
US05723450

Reaction notes

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