HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyrrolidinol, 2-methyl-, hydrochloride (1:1), (2R,3S)- → HCID 57554919, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyrrolidinol, 2-methyl-, hydrochloride (1:1), (2R,3S)- | HCID 55287363 | — |
| Reactant | [5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonyl]-piperidin-4-one | HCID 67314190 | — |
| Product | HCID 57554919 | HCID 57554919 | — |
Reaction Steps
The title compound was prepared from 1-[5-Cyclopropyl-3-methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonyl]-piperidin-4-one (Example 181B) and (2R,3S)-2-methyl-pyrrolidin-3-ol hydrochloride (example 187A) in direct analogy to the general procedure used in example 129. MS: 477.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977358B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-68bd732e08984a6fb9c89d0d92e502e3 |
| Source note | uspto-grants-2011_07 |