HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-amino-3-nitrobenzoate → 2,3-Diaminobenzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-amino-3-nitrobenzoate | HCID 607264 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2,3-Diaminobenzoic acid methyl ester | HCID 571825 | 93.5% |
Reaction Steps
A mixture of methyl-2-amino-3-nitrobenzoate (530 mg) and 10% Pd/C (55 mg) in EtOH (10 ml) was stirred under an atmosphere of hydrogen at ambient temperature for 16 h. The catalyst was removed by filtration through Celite and the filtrate reduced in vacuo to give methyl 2,3-diaminobenzoate (420 mg) as a yellow/brown oil which solidified on standing.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977477B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-3eb3a4dffdde4ef1b809145830eb4faa |
| Source note | uspto-grants-2011_07 |