tert-Butyl isocyanate → HCID 178449560, compound

Participants

Reaction Steps

A mixture or 3-(1H-Benzimidazol-2-yl)-1H-pyrazol-4-ylamine (100 mg, 0.50 mmol), tert-butyl isocyanate (60 ul, 0.60 mmol) in DMF (5 ml) was stirred at ambient temperature for 4 h. The mixture was reduced in vacuo. The residue was purified by preparative LC/MS, and following evaporation, gave 52 mg of the title compound as a white solid (35%). (LC/MS: Rt 2.61, [M+H]+ 299.15).

Provenance & Evidence