HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178499180, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 178470496 | HCID 178470496 | — |
| Reactant | HCID 178524956 | HCID 178524956 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178499180 | HCID 178499180 | — |
Reaction Steps
The compound was prepared in a manner analogous to 4-nitro-1H-pyrazole-3-carboxylic acid ethyl ester (Example 16A) using 4-nitro-1H-pyrazole-3-carboxylic acid (100 g, 636 mmol), thionyl chloride (55.5 ml, 764 ml) and MeOH (750 ml), instead of EtOH. 4-Nitro-1H-pyrazole-3-carboxylic acid methyl ester was obtained as an off-white solid (109 g, 100%). (LC/MS (acidic method): Rt 1.82 min, [M+H]+ 172).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977477B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-4628d4f4e7e24ca0a743b5009fa72fe1 |
| Source note | uspto-grants-2011_07 |