2,3-Difluoro-4-methoxybenzyl bromide → 4-chloro-N-[(2,3-difluoro-4-methoxyphenyl)methyl]-N-(5,5-difluoro-2-oxoazepan-3-yl)benzenesulfonamide
Reaction equation
[Br:22][CH2:23][c:24]1[c:25]([F:33])[c:26]([F:32])[c:27]([O:30][CH3:31])[cH:28][cH:29]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[CH2:23][c:24]2[c:25]([F:33])[c:26]([F:32])[c:27]([O:30][CH3:31])[cH:28][cH:29]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-6b04faecab6a4d65b2bf61ff9cf9c9bb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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