Ethanol → HCID 67315765, compound

Participants

Reaction Steps

Under a nitrogen stream 415 mg (3.77 mmol, 1.1 equivalents) of 5-methyl-2-furaldehyde, 10 ml of ethanol, 1.0 g (3.43 mmol, 1.0 equivalent) of 4-[(4-dipropylaminobutyl)amino]methylbenzylamine (5a), and 3 g of anhydrous sodium sulfate were charged in a 50 ml recovery flask and reacted at 25° C. for 20 hours. After completion of the reaction, the reaction solution was filtered, and concentrated, thereby obtaining 1.32 g of {(4-dipropylaminobutyl)-[4-(5-methylfuran-2-ylmethylidene)aminomethylbenzyl]}amine (26) as a reddish brown oily substance (yield: 100%). [HPLC: 95.7% (HPLC measurement conditions C)]

Provenance & Evidence