Methyl 2-methyl-5-nitrobenzoate → Methyl 5-Amino-2-methylbenzoate

Participants

Reaction Steps

Compound 497 (26.5 g, 135.78 mmol) in ethanol (200 ml) was hydrogenated under 1 atmosphere at room temperature in the presence of Pd/C 5% (2.00 g) for 3 h. After reaction, the catalyst was filtered off. The filtrate was concentrated in vacuo, providing the title compound as a brownish oil.

Provenance & Evidence