HCID 58677534, compound → HCID 58677522, compound

Participants

Reaction Steps

Compound 307 (46 mg, 0.1 mmol) was dissolved in EtOH (5 mL), flushed with argon and added Pd/C (cat. amount). The flask was purged with H2 for 2 min. and stirred under an H2-atmosphere at RT for 1 h. The reaction mixture was filtered through Celite and concentrated in vacuo. Purified by continuously gradient flash chromatography using DCM/MeOH (v:v=100:0 to 95:5) as the eluent, affording the title compound as a yellow oil. 13C NMR (DMSO-d6) δ 196.3, 158.9 (dd), 156.2, 155.6 (dd), 154.2, 150.8, 142.2, 135.6, 131.1, 127.0 (dd), 125.2, 124.8 (dd), 114.5, 112.2, 111.6 (dd), 109.7, 104.8 (dd), 104.0, 96.9, 64.6, 57.2, 32.1, 17.9

Provenance & Evidence