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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1012803Generated: October 30, 2026

Cyclobutanecarbonyl chloride → HCID 67314693, compound

https://huagongshe.com/reaction/1012803

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutanecarbonyl chlorideHCID 78705—
ReactantHCID 67312996HCID 67312996—
ProductHCID 67314693HCID 67314693—

Reaction Steps

50 mg (0.12 mmol) of 7-(3-aminophenyl)-N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzothiophene-2-carboxamide hydrochloride (Example 21) and 28.6 mg (0.24 mmol) of cyclobutanecarbonyl chloride are reacted together by general method F. 38 mg (61.3% of theory) of the title compound are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977485B2
Source datasetuspto-grants-2011_07
ORD IDord-10ccb38d646e4f108e9d4ee71d327039
Source noteuspto-grants-2011_07