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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1012839Generated: October 29, 2026

Isoxazole-5-carbonyl chloride → HCID 67314513, compound

https://huagongshe.com/reaction/1012839

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoxazole-5-carbonyl chlorideHCID 2736707—
ReactantHCID 58675161HCID 58675161—
ProductHCID 67314513HCID 67314513—

Reaction Steps

50 mg (0.14 mmol) of 7-(3-aminophenyl)-N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-2-carboxamide (Example 114) and 36.4 mg (0.28 mmol) of 5-isoxazolecarbonyl chloride are reacted together by general method F. 39.6 mg (53.3% of theory) of the title compound are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977485B2
Source datasetuspto-grants-2011_07
ORD IDord-93b9be56fd434f058edef1a2e164c3a8
Source noteuspto-grants-2011_07