p-Toluenesulfonic acid → HCID 86606712, compound

Participants

Reaction Steps

95.9 mg (0.25 mmol) of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-(2-methoxyphenyl)-1-benzofuran-2-carboxamide (Example 130) are dissolved in 2 ml of methanol. After addition of 49.2 mg (0.25 mmol) of p-toluenesulphonic acid, the mixture is concentrated and the residue is dried under high vacuum. 143 mg (99.4% of theory) of the title compound are obtained.

Provenance & Evidence