HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carbaldehyde → HCID 11998933, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carbaldehyde | HCID 11593591 | — |
| Reactant | 4-Methoxy-1,3-benzothiazole | HCID 12631858 | — |
| Reactant | HCID 57699455 | HCID 57699455 | — |
| Product | HCID 11998933 | HCID 11998933 | — |
Reaction Steps
Using the same method as for Example 23, steps 23.a to 23.f, the title compound was synthesised from 4-methoxybenzothiazole, (3R,6S)-(6-formyl-tetrahydro-pyran-3-yl)-carbamic acid tert-butyl ester and 3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carbaldehyde. After chromatography on SiO2 (EtOAc/MeOH 9:1 +1% NH4OH) and crystallisation from ether/MeOH, a yellowish solid (30 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07981886B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-1dc32f683a7a420a95b8dd49633b3d6c |
| Source note | uspto-grants-2011_07 |