Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 86604943 | HCID 86604943 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67316971 | HCID 67316971 | — |
Reaction Steps
The product of step b) (50 mg, 0.13 mmol) was dissolved in 4 mL THF. NaOH (0.52 mL of 1 M aq) was added and the reaction was heated to 60° C. for 3 days. The reaction was cooled, acidified with 1 M HCl, and extracted into DCM. Concentration gave the sub-title product as a yellow oil. MS: ESI (negative): 318 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07981912B2 |
|---|
| Source dataset | uspto-grants-2011_07 |
|---|
| ORD ID | ord-5b5765fbb56a40e1a0138bc29234fb67 |
|---|
| Source note | uspto-grants-2011_07 |
|---|
