HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopropionitrile → {3-[2-(Cyano-methyl-methyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-5-methyl-indol-1-yl}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopropionitrile | HCID 140538 | — |
| Reactant | [3-(1,1-Dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-5-methyl-indol-1-yl]-acetic acid tert-butyl ester | HCID 67317704 | — |
| Product | {3-[2-(Cyano-methyl-methyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-5-methyl-indol-1-yl}-acetic acid | HCID 59753811 | — |
Reaction Steps
The title compound was prepared by the method described for example 14 using the product from example 2, step c) and 2-bromo-propionitrile. MS: ESI (negative): 408 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07981912B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-da3c382acc0840e6921ebaef79501a33 |
| Source note | uspto-grants-2011_07 |