Isoxazole, 4-(chloromethyl)-5-methyl-3-phenyl- → HCID 11519729, compound

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Reaction Steps

The title compound was prepared by the method described for example 14 using the product from example 6, step c) and 4-chloromethyl-5-methyl-3-phenyl-isoxazole. 1H NMR (DMSO-d6) 7.99-7.91 (m, 1H), 7.69-7.60 (m, 2H)), 7.43 (d, J=8.7 Hz, 1H), 7.36 (d, J=7.2 Hz, 2H), 7.23-6.75 (m, 6H), 5.94 (s, 1H), 4.96 (s, 2H), 4.33 (d, J=14.1 Hz, 1H), 4.07 (d, J=14.1 Hz, 1H), 3.30 (s, 3H), 2.41 (s, 3H); MS: ESI (negative): 560, 562 (M−H).

Provenance & Evidence