Potassium Carbonate → HCID 68905782, compound

Participants

Role	Name	HCID	Charge
Reactant	Potassium Carbonate	HCID 11430	—
Reactant	1-Chloroethyl chloroformate	HCID 521305	—
Reactant	6-Benzyl-4,5,6,7,7a,8-hexahydro-3bH-1-thia-6-aza-cyclopenta[alpha]indene	HCID 131727038	—
Solvent	1,1-Dichloroethane	HCID 6365	—
Product	HCID 68905782	HCID 68905782	60%

Reaction Conditions

Temperature	22 °C

Reaction Steps

The product from step g) (279 mg, 1.04 mmol) in dichloroethane (5.2 ml) was treated with K2CO3 (574 mg, 4.16 mmol) and Ace-Cl (451 μl, 4.16 mmol) at 80° C. for 16 hours. Next, the reaction mixture was filtered, concentrated and the residue was dissolved in anhydrous MeOH (25 ml) and stirred for 1 hour at 22° C. The MeOH was concentrated and triturated with ether to give 135 mg (60%) of the subtitle compound. MS calculated for C10H13NS+H 180, observed 180.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07981919B2
Source dataset	uspto-grants-2011_07
ORD ID	ord-329d15251dd842b0a8fd5e6373e50274
Source note	uspto-grants-2011_07