Lithium Chloride → HCID 67206860, compound

Participants

Reaction Conditions

Reaction Steps

Lithium chloride (2.77 g, 0.066 mol) was added to the product of step e) (5.8 g, 0.016 mol) in 200 mL of THF followed by the addition of 2.0 M lithium borohydride (58 mL, 0.115 mol). The reaction was stirred overnight at 60° C. and was then cooled to room temperature. The reaction mixture was filtered through Celite, diluted with 100 mL of water and was extracted with ethyl acetate (3×150 mL). The combined ethyl acetate extracts were dried (MgSO4) and the solvent evaporated in vacuo to give the subtitle compound that was used without further purification. MS calculated for C16H23NO3S +H: 310, observed: 310.

Provenance & Evidence