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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1013595Generated: October 26, 2026

Methyl Isocyanate → (R)-1-[6-(3-Fluoro-benzenesulfonyl)-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl]-3-methyl-urea

https://huagongshe.com/reaction/1013595

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl IsocyanateHCID 12228—
ReactantC-[6-(3-Fluoro-benzenesulfonyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]methylamineHCID 59021794—
Product(R)-1-[6-(3-Fluoro-benzenesulfonyl)-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl]-3-methyl-ureaHCID 46890157—

Reaction Steps

(R)-1-[6-(3-Fluoro-benzenesulfonyl)-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl]-3-methyl-urea was prepared by treatment of C-[6-(3-Fluoro-benzenesulfonyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-methylamine with methyl isocyanate according to the procedure of Najer et al.; Bull. Soc. Chim. Fr.; 1069-1071 (1957).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07981923B2
Source datasetuspto-grants-2011_07
ORD IDord-abfcfbef35b0440d8e0ce26229a581dc
Source noteuspto-grants-2011_07