(Pyrimidin-5-yl)boronic acid → 3-(3-Fluoro-4-pyridinyl)-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine

HRID 101414Notes

Reaction equation

HRID 101414 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8]2([c:18]3[c:19]([F:24])[cH:20][n:21][cH:22][cH:23]3)[N:9]=[C:10]([NH2:17])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1.[n:25]1[cH:26][n:27][cH:28][c:29]([B:31]([OH:32])[OH:33])[cH:30]1>>[c:2]1(-[c:29]2[cH:28][n:27][cH:26][n:25][cH:30]2)[cH:3][c:4]([C:8]2([c:18]3[c:19]([F:24])[cH:20][n:21][cH:22][cH:23]3)[N:9]=[C:10]([NH2:17])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 2795193(Pyrimidin-5-yl)boronic acidHCID 595962811-(3-Bromophenyl)-1-(3-fluoropyridin-4-yl)-1H-isoindol-3-amine

Product 1

HCID 595963033-(3-Fluoro-4-pyridinyl)-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine

Sources & evidence

ORD record
ord-9f935ac0e97f4ecdbce13bedf6ac0c5c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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