HCID 59441803, compound → HCID 59441666, compound

Participants

Reaction Steps

A solution of N,N-dimethyl-2-[6-(methyloxy)-5-nitro-2,3-dihydro-1H-indol-1-yl]-2-oxoethanamine (0.16 g, 1.72 mmol) in absolute ethanol (50 mL) was maintained under 45 psi H2(g) with catalytic 10% Pd/C for 12 hours. The catalyst was removed by vacuum filtration through a celite pad and rinsed with methanol. The filtrate was concentrated under reduced pressure and dried under high vacuum to provide 1-[(dimethylamino)acetyl]-6-(methyloxy)-2,3-dihydro-1H-indol-5-amine. This was then carried forward without any further purification. ESIMS (M+H)+=250.

Provenance & Evidence