Methanol → 1-[2-Methoxy-5-(naphthalene-1-sulfonyl)-phenyl]-piperazine

HRID 101452Notes

Reaction equation

HRID 101452 reaction equation
[CH3:37][OH:38].[F:3][C:4]([F:5])([F:6])[C:34]([N:7]1[CH2:8][CH2:9][N:10]([c:13]2[c:14]([O:32][CH3:33])[cH:15][cH:16][c:17]([S:19](=[O:20])(=[O:21])[c:22]3[cH:23][cH:24][cH:25][c:26]4[cH:27][cH:28][cH:29][cH:30][c:31]34)[cH:18]2)[CH2:11][CH2:12]1)=[O:35].[Na+:2].[OH-:1].[OH2:36]>>[NH:7]1[CH2:8][CH2:9][N:10]([c:13]2[c:14]([O:32][CH3:33])[cH:15][cH:16][c:17]([S:19](=[O:20])(=[O:21])[c:22]3[cH:23][cH:24][cH:25][c:26]4[cH:27][cH:28][cH:29][cH:30][c:31]34)[cH:18]2)[CH2:11][CH2:12]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 121366542,2,2-Trifluoro-1-{4-[2-methoxy-5-(naphthalene-1-sulfonyl)-phenyl]-piperazin-1-yl}-ethanone

Product 1

HCID 69186961-[2-Methoxy-5-(naphthalene-1-sulfonyl)-phenyl]-piperazine

Sources & evidence

ORD record
ord-4389efbd94cf471497b0a2d74bc707b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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