1-[3-(Trifluoromethyl)phenyl]-1,4-diazepane → 3-{4-[4-(3-Trifluoromethyl-phenyl)-[1,4]diazepan-1-yl]-cyclohexyl}-6-fluoro-1H-indole
Reaction equation
[F:18][c:19]1[cH:20][cH:21][c:22]2[c:23]([CH:28]3[CH2:29][CH2:30][C:31](=[O:34])[CH2:32][CH2:33]3)[cH:24][nH:25][c:26]2[cH:27]1.[F:1][C:2]([c:3]1[cH:4][c:5]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14][CH2:15]2)[cH:6][cH:7][cH:8]1)([F:16])[F:17]>>[F:1][C:2]([c:3]1[cH:4][c:5]([N:9]2[CH2:10][CH2:11][N:12]([CH:31]3[CH2:30][CH2:29][CH:28]([c:23]4[c:22]5[cH:21][cH:20][c:19]([F:18])[cH:27][c:26]5[nH:25][cH:24]4)[CH2:33][CH2:32]3)[CH2:13][CH2:14][CH2:15]2)[cH:6][cH:7][cH:8]1)([F:16])[F:17]Participants
3
Sources & evidence
- ORD record
- ord-5247e63659db4159b390ce110c64dbbd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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