化工社化工社 化学情報印刷レポート · 研究参考用
Oxirane, 2-propyl- → 2-(2-(3-(2-Hydroxypentyloxy)phenoxy)ethyl)isoindoline-1,3-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Oxirane, 2-propyl- | HCID 13853 | — |
| 反応物 | 2-[2-(3-Hydroxy-phenoxy)-ethyl]-isoindole-1,3-dione | HCID 58027534 | — |
| 生成物 | 2-(2-(3-(2-Hydroxypentyloxy)phenoxy)ethyl)isoindoline-1,3-dione | HCID 67317024 | — |
反応手順
Alkylation reaction of phenol 24 with 1,2-epoxypentane gave 2-(2-(3-(2-hydroxypentyloxy)phenoxy)ethyl)isoindoline-1,3-dione as yellow oil. Yield (1.1 g, 84%): 1H NMR (400 MHz, CDCl3) δ 7.98 (d, J=6.8 Hz, 1H), 7.44-7.56 (m, 2H), 7.12-7.16 (m, 1H), 6.68-6.73 (m, 1H), 6.46-6.52 (m, 3H), 4.10 (t, J=5.2 Hz, 2H), 3.90-4.0 (m, 2H), 3.77-3.82 (m, 3H), 1.32-1.56 (m, 4H), 0.94 (t, J=6.8 Hz, 3H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07982071B2 |
| 出典データセット | uspto-grants-2011_07 |
| ORD ID | ord-71847a4d1d2e471b8fd522cc0ebc5bb3 |
| 出典メモ | uspto-grants-2011_07 |