Acetic Anhydride → N-[2-(4-chlorophenyl)ethyl]acetamide

HRID 1015011Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][NH2:10])=[CH:4][CH:3]=1.[C:11](OC(=O)C)(=[O:13])[CH3:12]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][NH:10][C:11](=[O:13])[CH3:12])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 674302-(4-Chlorophenyl)ethylamine

Product 1

HCID 9877644N-[2-(4-chlorophenyl)ethyl]acetamide

Procedure

In close analogy to the procedure described above, 2-(4-chloro-phenyl)-ethylamine is reacted with acetic anhydride to provide the title compound.

Sources & evidence

ORD record: ord-97c179e1d88442ad9dfd74df8298c1ec
Source dataset: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07985753B2

Reaction notes

Loading…