Acetic Anhydride → N-[2-(2-chlorophenyl)ethyl]acetamide

HRID 1015012Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][NH2:10].[C:11](OC(=O)C)(=[O:13])[CH3:12]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][NH:10][C:11](=[O:13])[CH3:12]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 831172-(2-Chlorophenyl)ethylamine

Product 1

HCID 10397817N-[2-(2-chlorophenyl)ethyl]acetamide

Procedure

In close analogy to the procedure described above, 2-(2-chloro-phenyl)-ethylamine is reacted with acetic anhydride to provide the title compound.

Sources & evidence

ORD record: ord-65662801701d46db909b4dfa0a89661e
Source dataset: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07985753B2

Reaction notes

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