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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1015030Generated: October 31, 2026

Phosphorus oxide (P4O10) → 7-Chloro-3,4-dihydro-1-methylisoquinoline

https://huagongshe.com/reaction/1015030

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxide (P4O10)HCID 14812—
ReactantN-[2-(4-chlorophenyl)ethyl]acetamideHCID 9877644—
Product7-Chloro-3,4-dihydro-1-methylisoquinolineHCID 11095213—

Reaction Steps

In close analogy to the procedure described above, N-[2-(4-chloro-phenyl)-ethyl]-acetamide is reacted with phosphorus pentoxide to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07985753B2
Source datasetuspto-grants-2011_07
ORD IDord-9f453720fe8644fe88ad7d48eccc2325
Source noteuspto-grants-2011_07