Boronic Acid → HCID 58416321, compound

HRID 1015073Notes

Reaction equation

HRID 1015073 reaction equation
Br[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][NH:6][CH:7]2[CH3:12].B(O)O>>[CH3:12][CH:7]1[C:8]2[C:3](=[C:2]([C:3]3[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=3)[CH:11]=[CH:10][CH:9]=2)[CH2:4][CH2:5][NH:6]1

Participants

3

Reactant 2

HCID 61668Boronic AcidHCID 596625945-Bromo-1,2,3,4-tetrahydro-1-methylisoquinoline

Product 1

HCID 58416321HCID 58416321, compound

Procedure

In close analogy to the procedure described above, 5-Bromo-1-methyl-1,2,3,4-tetrahydro-isoquinoline is reacted with the corresponding boronic acid to provide the title compound.

Sources & evidence

ORD record
ord-48218c4b354b4bddbe45eb6e2320b470
Source dataset
uspto-grants-2011_07
Patent number
US07985753B2

Reaction notes

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